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Speaker Location: UBC (Michael Smith Laboratories, MSL 102)
Live Stream: SFU (Big Data Hub, ASB 10900)
Featured Speaker: Dr. Sabrina Leslie, Associate Professor, Michael Smith Labs and Physics Department, University of British Columbia
Talk title: Multi-scale Seeing-Is-Believing Platform and Investigations: Imaging and Advancing RNA Vaccines and Genetic Medicines
Talk Abstract: Everything you experience, from the smoothness of your sunscreen to the effectiveness of your vaccine, ultimately comes from the interactions of single molecules. In this talk, we share our "tether-free" single-molecule platform for directly imaging the motion and interactions of single molecules as well as single cells in physiological conditions. We share how this approach can be used to investigate, quantitate and understand the detailed properties of, for instance, lipid nanoparticles containing mRNA cargo and thereby help standardize and improve new classes of nanomedicines. "Seeing is Believing": the inspiration of our imaging work is to apply new quantitative analyses to investigate and unlock the intricate dynamics of nanomedicines in the complex conditions inside living cells, with back-to-back experiments in precisely controlled femto volumes in our microfluidic imaging devices.
Trainee Speaker: Jordan Yu (PhD Candidate, Tam and Frangou Lab, UBC)
Talk Title: Brain-Age Prediction: Systematic Evaluation of Site Effects, and Sample Age Range and Size
Source: VanBUG