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New publication: Judith Mank and Elizabeth Rideout. Development. See abstract...

October 18, 2021

Judith E. Mank and Elizabeth J. Rideout. 2021. Developmental mechanisms of sex differences: from cells to organisms. Development,, 148 (19): dev199750.

Abstract
Male-female differences in many developmental mechanisms lead to the formation of two morphologically and physiologically distinct sexes. Although this is expected for traits with prominent differences between the sexes, such as the gonads, sex-specific processes also contribute to traits without obvious male-female differences, such as the intestine. Here, we review sex differences in developmental mechanisms that operate at several levels of biological complexity – molecular, cellular, organ and organismal – and discuss how these differences influence organ formation, function and whole-body physiology. Together, the examples we highlight show that one simple way to gain a more accurate and comprehensive understanding of animal development is to include both sexes.

Department of Zoology
4200 - 6270 University Blvd.
Vancouver, BC Canada V6T 1Z4
604 822 2131
E-mail info@zoology.ubc.ca
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