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The best way to find out what experiments we're planning is to read our grant proposals. Here
are
links to our latest proposal which we have just submitted to CIHR (The
Canadian Institutes for Health Research). This proposal aims to
investigate the consequences of DNA uptake and transformation in Haemophilus influenzae and other Gram-negative bacteria. We are all currently working on prelimary data for this
proposal. Here
are links to the proposals we have just submitted to Cystic Fibrosis
Canada, proposing to use next generation sequencing to characterize H. influenzae populations in vivo, and
to NSERC (National Sciences and Engineering Research Council of
Canada), proposing to test whether uptake specificity is a generalised
phenomenon.
The second proposal addresses the role of the Sxy transcriptional activator, considering both how the sxy gene is regulated and how the Sxy protein works with CRP to activate genes with CRP-S sites in their promoters. Its title is "Regulation of CRP-S promoters in H. influenzae and E. coli.". This proposal was successfully funded in 2007. We have achieved most of the goals outlined in this proposal.
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